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Lawrence C.
Smith, D.M.V., Ph.D. Phone 450-773-8521, ext 8463 smithl@medvet.umontreal.ca
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Recent results (2000-2001)
Regulation of the expression of housekeeping and developmentally regulated genes are altered in embryos derived from somatic cell clones; The expression of imprinted genes is altered in donor cells treated by cell cycle synchronization protocols; Meirelles, F.V., Bordignon, V., Watanabe, Y., Watanabe,
M., Dayan, A., Lôbo, R. and Smith, L.C.
(2001) Complete replacement of the mitochondrial genotype in a Bos
indicus calf reconstructed by nuclear transfer to a Bos
taurus oocyte. Genetics 158:
351-356; Bordignon, V., Clarke, H.J. and Smith,
L.C. (2001) Factors controlling the loss of immunoreactive somatic histone
H1 from blastomere nuclei in oocyte cytoplasm: a potential marker of nuclear Develp.
Biol. 233: 192-203; Betts, D.H., Bordignon, V., Hill, J.R., Winger, Q.,
Westhusin, M.E., Smith, L.C., King,
W.A. (2001) Reprogramming of telomerase activity and rebuilding of telomere
length in cloned cattle. Proc. Natl. Acad.
Sci. USA
98: 1077-1082; His team
From left to right : (2nd row) Senan Baqir, Christian Vigneault, Jacinthe Therrien, Carmen Léveillée, José Henrique Fortes Pontes; (1st row) Jean Durocher, DMV from the technological services at Alliance Boviteq, Vilceu Bordigon and Edmir Da Silva Nicola
Senan Baqir, Ph.D. Student |
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