Accueil site FMV Plan de ce sous-site Bottin de l'U de m Plan campus Saint-Hyacinthe Rechercher sur le site de la FMV
Version française
Version española
Home page
Researchers
Projects
Graduate studies
Publications
Science for all
Seminars
Comments
Site plan

 

Lawrence C. Smith, D.M.V., Ph.D.
Phone 450-773-8521, ext 8463
smithl@medvet.umontreal.ca

 

Recent results (2000-2001)

  • Production of transgenic clones derived by nuclear transfer using transfected somatic donor nuclei;

  • Birth of Starbuck II, bovine cloned derived from subcutaneous fibroblast recovered from the legendary bull Hanoverhill Starbuck two years before its death;

  • Regulation of the expression of housekeeping and developmentally regulated genes are altered in embryos derived from somatic cell clones;

  • The expression of imprinted genes is altered in donor cells treated by cell cycle synchronization protocols;

Meirelles, F.V., Bordignon, V., Watanabe, Y., Watanabe, M., Dayan, A., Lôbo, R. and Smith, L.C. (2001) Complete replacement of the mitochondrial genotype in a Bos indicus calf reconstructed by nuclear transfer to a Bos taurus oocyte. Genetics 158: 351-356;

Bordignon, V., Clarke, H.J. and Smith, L.C. (2001) Factors controlling the loss of immunoreactive somatic histone H1 from blastomere nuclei in oocyte cytoplasm: a potential marker of nuclear Develp. Biol. 233: 192-203;

Betts, D.H., Bordignon, V., Hill, J.R., Winger, Q., Westhusin, M.E., Smith, L.C., King, W.A. (2001) Reprogramming of telomerase activity and rebuilding of telomere length in cloned cattle. Proc. Natl. Acad. Sci. USA 98: 1077-1082;  

His team

From left to right : (2nd row) Senan Baqir, Christian Vigneault, Jacinthe Therrien, Carmen Léveillée, José Henrique Fortes Pontes; (1st row) Jean Durocher, DMV from the technological services at Alliance Boviteq, Vilceu Bordigon and Edmir Da Silva Nicola

Senan Baqir, Ph.D. Student
Dr Vilceu Bordignon, dvm, PhD
Dr Marcia Couto, dvm, Masters Degree Student
France Filion,
Masters Degree Student, Research assistant
Carmen Léveillée, Technician
Dr Edmir Nicola, dvm, Ph.D. Student
Dr Henrique Pontes, dvm, Masters Degree Student
Jacinthe Thérien, Research Assistant
Christian Vignault, BSc. Student