Erythrophagocytosis/Hemosiderophagocytosis
BAL, Equine,
original magnification x1000
Author : Dr Pierre Hébert
Translation by Dr. Khyali R. Mittal
Erythrophagocytosis/Hemosiderophagocytosis
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BAL, Equine, Author : Dr Pierre Hébert |
Description: macrophages having phagocytosed erythrocytes (red arrow) as well as hemosiderin (blue arrow). Staining with Prussian Blue is necessary for confirming the nature of the hemosiderin pigments. Hemosiderin is a reserve of iron which is not easily mobilized and originates from the degraded red blood cells. The presence of hemosiderophagocytosis in the bronchoalveolar lavage (BAL) is suggestive of a chronic intrapulmonary blood loss. A very large number of race horses will be showing the presence of hemosiderophagocytosis. In dogs and cats, the hemosiderophagocytes and erythrophagocytes present in the BAL are also called "cardiac cells" and are synonym with cardiac insufficiency. |
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