Perianal  Gland Adenoma

The perianal gland adenoma is a benign tumour of the anal glands in the dog. The cells have a characteristic appearance in cytology: they have a cytoplasm which is moderately abundant and which contains fine granules. The cells’ nuclei have a uniform appearance and are located centrally or slightly eccentrically. The nuclei may contain a single round nucleolus. Since these cells are of the epithelial type, they will commonly be arranged in clusters due to the intercellular bridging which causes them to adhere together. The intercellular bridges are visible at the bottom of the cluster of cells on the right (below) as a fine, clear stripe between the cells. For more on the cytological appearance of other types of secretory cells, click here.

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