Informe Anual version francés=500k

Prospecto (version francès, version inglés)

Publicaciones 
   

Arosh JA, J Parent, P Chapdelaine, J. Sirois, MA Fortier. (2002)  Expression of cyclooxygenases 1 and 2 and PGE synthase in bovine endometrial tissue during the estrous cycle.  Biol Reprod 67: 161-169.

Baqir S., Zhou Q., Renard J.-P., and Smith L.C. (2002) Abherrant expression profile of imprinted genes in cloned mouse embryos reconstructed with ES cells treated with 5AzaC or TSA. Biol Reprod 66: 361.

Baqir, S, and Smith, L.C. (2001) Acetylation interferes with the expression of imprinted genes in mouse embryonic stem cells. Theriogenology 55:410.

Betts, D.H., Bordignon, V., Hill, J.R., Winger, Q., Westhusin, M.E., Smith, L.C., King, W.A. (2001) Reprogramming of telomerase activity and rebuilding of telomere length in cloned cattle. Proc. Natl. Acad. Sci. USA 98: 1077-1082.

Blondin, P., Sirard,M.A., Morin,N., Carbonneau,G., Brisson,C. and Bousquet, D.  (2001)  Effect of freeze-thaw and biopsy on bovine embryos produced in vitro in synthetic oviductal fluid (SOF) medium., Theriogenology 55(1) :301.

Boerboom D, J Sirois. (2001)  Equine P450 cholesterol side-chain cleavage and 3ß-hydroxysteroid dehydrogenase/delta 5-4 isomerase: Molecular cloning and regulation of their messenger ribonucleic acids in equine follicles during the ovulatory process.  Biol Reprod 64:206-215.

Bordignon V. and Smith L.C. (2002) Bovine embryos reconstructed with somatic cells arrested at G0/G1 with metaphase oocytes or cycling with telophase host oocytes show similar developmental potential. Theriogenology 57 : 400.

Bordignon, V., Clarke, H.J. and Smith, L.C. (2001) Factors controlling the loss of immunoreactive somatic histone H1 from blastomere nuclei in oocyte cytoplasm: a potential marker of nuclear Develp. Biol. 233: 192-203.

Bordignon, V., Keystone, R., Lazaris, A., Keefer, C. and Smith, L.C. (2001) Transgenic cloned calves derived from in vitro transfected somatic cells using telophase- and metaphase-enucleated host oocytes. Theriogenology 55:257.

Boutemmine D, N Bouchard, D Boerboom, HE Jones, AK Goff, M Doré, J Sirois.  (2002)  Molecular characterization of canine prostaglandin G/H synthase-2 and regulation in prostatic adenocarcinoma cells in vitro.  Endocrinology 143: 1134-1143.

Buratini J, Teixeira AB, Glapinski VF, Barros CM & Price CA (2002) Fibroblast growth factor receptor-3C and -4 gene expression in bovine follicles. International Embryo Transfer Society, Foz do Iguacu, Brazil. Theriogeneology 57:601.

Carrière PD, Kohram H, Price CA, Durocher J & Guilbault LA (2002) Effects of delaying the LH surge and altering LH secretion on plasma hormones and embryos production in heifers superovulated with FSH  Can. J. Anim. Sci. 82:357-366.

Daneau I, Pilon N, Boyer A, Behdjani R, Overbeek PA, Viger R, Lussier J, Silversides DW.  (2002) The porcine SRY promoter is transactivated within a male genital ridge environment.  Genesis 33:170-180.

Gévry, N. and Murphy, B.D. (2002) The role and regulation of the Niemann-Pick C-1 gene in adrenal steroidogenesis.  Endocrine Research 28:407-416.

Gévry, N., Lacroix, D., Song, J-H., Pescador, N., Dobias, M., and Murphy, B.D.  (2002. Porcine Niemann Pick-C1 protein is expressed in steroidogenic tissues and modulated by 3’5’-cyclic adenosine monophosphate.  Endocrinology 143:708-16.

Gévry, N.Y., Lalli, E., Sassone-Corsi, P., and Murphy, B.D. (2002)  Regulation of Niemann-Pick C1 gene expression by the 3’5’ cyclic adenosine monophosphate pathway in steroidogenic cells.  Molec. Endocrinol. (sous presse)

Goff AK. (2002) Embryonic signals and survival. Reproduction in Domestic Animals. 37, 133-139

Joubert P, Silversides DW, Lavoie JP. (2001) Equine neutrophils express mRNA for tumour necrosis factor-alpha, interleukin (IL)-1beta, IL-6, IL-8, macrophage-inflammatory-protein-2 but not for IL-4, IL-5 and interferon-gamma. Equine Vet J. 33(7):730-3.

Lajoie S, J Sirois, M Doré. (2002)  Induction of prostaglandin G/H synthase-2 in porcine gastric ulcers. J Histochem Cytochem 50: 923-934.

Liu J, Antaya M, Goff AK, Boerboom D, Silversides DW, Lussier JG, Sirois J.  (2001)  Molecular characterization of bovine prostaglandin G/H synthase-2 and regulation in uterine stromal cells.  Biol. Reprod. 64:983-991.

Lopez, F., Desmarais, J, Gévry N.Y., Ledoux, S. and Murphy B.D. (2002)  Expression of vascular endothelial growth factor (VEGF) and receptors Flt-1 and KDR during the peri-implantation period in the mink (Mustela vison). Biol. Reprod (sous presse).

Martel Kennes Y., Murphy, B.D., Pothier, F., Palin, M-F. (2001) Characterization of swine leptin gene polymorphisms and their association with production traits.  Animal Genetics 32:215-218.

Meirelles, F.V., Bordignon, V., Watanabe, Y., Watanabe, M., Dayan, A., Lôbo, R. and Smith, L.C. (2001) Complete replacement of the mitochondrial genotype in a Bos indicus calf reconstructed by nuclear transfer to a Bos taurus oocyte. Genetics 158: 351-356.

Methot D, vanKats JP, Lochard N, Tremblay F, Silversides DW, Reudelhuber TL. (2001) Development and application of a biological peptide pump for the study of the in vivo actions of angiotensin peptides. Am J Hypertens. 2001 Jun;14(6 Pt 2):38S-43S.

Murphy B.D., Lalli E., Walsh L.P., Liu Z., Soh J., Stocco, D.M. Sassone-Corsi P. (2001) Heat shock interferes with steroidogenesis by reducing transcription of the StAR gene.  Molec. Endocrinol. 15:1255-1263.

Murphy, B.D., Gévry, N, Ruiz-Cortés, Z.T., Côté, F. Downey, B.R. Sirois, J. (2001)  Formation and early development of the corpus luteum in pigs.  Reproduction Suppl. 58:47-63.

Onclin K, Murphy B, Verstegen J.P. (2002)  Comparisons of estradiol, LH and FSH patterns in pregnant and nonpregnant beagle bitches.  Theriogenology 57: 1957-1972

Parent J, P Chapdelaine, J Sirois, M Fortier. (2002)  Expression of microsomal prostaglandin E synthase in bovine endometrium : coexpression with cyclooxygenase type 2 and regulation by interferon-tau.  Endocrinology 143:2936-2943.

Pestili de Almeida EM, C Piché, J Sirois, M Doré. (2001)  Expression of cyclooxygense-2 in naturally-occurring squamous cell carcinomas in dogs.  J Histochem Cytochem 49:867-876.

Pimentel, A.M., Bordignon, V. and Smith L.C. (2002) Effect of meiotic resumption delay on in vitro maturation and parthenogenetic development of equine oocytes. Theriogenology 57 : 735.

Prescott G, Silversides DW, Chiu SML, Reudelhuber TL. (2000) Contribution of circulating renin to local synthesis of angiotensin peptides in the heart.  Physiological Genomics 4(1):67-73.

Robert,C., Gagné, D., McGraw,S., Bousquet, D., Barnes, F.L., Sirard, MA. (2001) Microarray study to identify gene expression associated exclusively to oocyte. Bio. Reproduction 64(1) : 90 (résumé).

Ruiz-Cortés, T.  Ledoux, S., and Murphy, B.D. (2002) El tejido graso regula la reproducción en los mamíferos.  Revista Orinoquia (sous presse).

Ruiz-Cortés, Z.T., Gévry, Martel-Kennes, Y.  N.Y. Downey, B.R., Palin, M-F. and Murphy, B.D. (2002)  Biphasic effects of leptin in porcine granulosa cells.  Biol. Reprod.  (Sous presse)

Sanford LM, Price CA, Leggee DG, Baker SJ & Yarney TA. (2002) Role of FSH, numbers of FSH receptors and testosterone in the regulation of inhibin secretion during the seasonal testicular cycle of the adult ram. Reproduction 123:269-280.

Silva J.M. & C.A. Price. (2002) Insulin and IGF-I are necessary for FSH-induced cytochrome P450 aromatase but not cytochrome P450 side-chain cleavage gene expression in oestrogenic bovine granulosa cells in vitro. J. Endocr. 174: 499-508

Silversides DW (2001) Le génome de l’homme et des espèces domestiques.  Le médecin vétérinaire du Québec 31(4):158-162.

Silversides DW, Pilon N, Behdjani R, Boyer A, Daneau I, Lussier J. (2001) Genetic manipulation of sex differentiation and phenotype in domestic animals.  Theriogenology 55:51-63..

Slimane W., Bordignon V., Léveillée C., Smith L.C. and King, W.A. (2002) X-chromosomal complement of donor cells and reconstructed embryos derived from them Theriogenology 57 : 451.

Smith, L.C., Bordignon, V, Couto, M.M., Garcia, S.M., Yamazaki, W. and Meirelles, F.V. (2002) Mitochondrial genotype segregation and the bottleneck. Reproductive BioMedicine Online 4: 248-255

Therien,I., Bousquet D., Manjunath,M. (2001) Effect of seminal phospholipid-binding proteins and follicular fluid on bovine sperm capacitation.  Biology of Reproduction 65(1) :41-51.

Uribe-Velásquez LF, Oba E, Souza MIL, Lara-Herrera LC, Villa-Velásquez H, Trinca LA & Price CA (2001) Follicular and hormonal events associated with the first-wave dominant follicle after treatment with PGF2alpha in sheep. Fourth International Congress on farm Animal Endocrinology, Parma, Italy. Abstract P4.

van Kats JP, Methot D, Paradis P, Silversides DW, Reudelhuber TL. (2001) Use of a biological peptide pump to study chronic peptide hormone action in transgenic mice: Direct and indirect effects of angiotensin II on the heart. J Biol Chem. 276(47):44012-7.

Zhou Q., Baqir S., Brochard V., Smith L.C. Renard J.-P. (2002) Donor nuclei are not well reprogrammed by nuclear transfer Biol Reprod 66: 345.

Bingtuan Wang

Comunicationes cientificas

Bédard J, Brûlé S, Price C, Silversides D, Lussier JG. 2001. Expression différentielle de la SERPIN-1bovine au cours de la dominance folliculaire ovarienne chez la vache. Journée de la recherche des biologistes en reproduction et développement du grand Montréal. Université de Montréal (novembre).

Bédard J, Brûlé S, Price C, Silversides DW, Lussier JG. 2001. Bovine SERPIN-1 : A gene differentially expressed during follicular development that is potentially involved in follicular dominance. 34th Annual meeting of the Society for the Study of Reproduction, Biology of Reproduction 64 Suppl.1 : 474 (juillet).

Bédard J, Brûlé S, Price C, Silversides DW, Lussier JG. 2001. bSerpin-1 : un gène différentiellement exprimé et potentiellement impliqué dans la dominance folliculaire. 69ième Congrès de l’Association canadienne française pour lavancement des sciences. Université de Sherbrooke, Sherbrooke, Québec (mai).

Behdjani R, Pilon N, Daneau I, Lussier JG, Silversides. 2001. DAX-1 transgene expression in adult and embryonic gonads. 34th Annual meeting of the Society for the Study of Reproduction, Biology of Reproduction 64 Suppl. 1 : 157 (juillet).

Boerboom D, DL Russell, JS Richards and J Sirois.  (2002)  Coordinated regulation of transcripts encoding ADAMTS-1 and progesterone receptor in equine preovulatory follicles. Biol. Reprod. 66 (suppl. 1):131.

Boyer A, Dornan S, Daneau I , Lussier JG, Silversides DW. 2001. Transgenic mouse expression model for DMRT-1 promotor. 34th Annual meeting of the Society for the Study of Reproduction, Biology of Reproduction 64 Suppl. 1 : 160 (juillet).

Boyer A, Dornan S, Lussier JG, Silversides DW. 2001. Expression d’un transgène rapporteur pour DMRT-1 dans les testicules de souris. Journée de la recherche des biologistes en reproduction et développement du grand Montréal. Université de Montréal (novembre).

Brown KA, D Boerboom, N Bouchard, J Lussier and J Sirois.  (2002)  Induction of 17b-hydroxysteroid dehydrogenase type 4 in equine preovulatory follicles during human chorionic gonadotropin-induced ovulation. Biol. Reprod. 66 (suppl. 1):130.

Brûlé S, Faure R, Bause E, Silversides DW, Lussier JG. 2001. Association of VASAP-60 in vesicular trafficking. 11th Winternational symposium. Canadian Society of Biochemistry and Molecular & Cellular Biology. Biochemistry and Cell Biology 79(5): 665 (janvier).

Côté F, M Doré, B Downey and J Sirois.  (2001)  Regulation of PGHS-2 in porcine preovulatory follicles in vivo.  Biol Reprod 64 (Suppl. 1): 161

Desmarais, J. , Bennett, R.D., Gévry N. and Murphy, B.D.  2002  The role of peroxisome-proliferator activated receptor-d (PPAR-d) in the process of implantation in the mink (Mustela vison).   Biol. Reprod. 66 (Suppl 1.): 123. This abstract was selected as one of six finalists in the competition for  trainee awards at the 2002 Society for the Study of Reproduction Annual Meeting.

Fayad T, Lévesque V, Sirois J, Silversides DW, Lussier JG. 2002. Identification de gènes différentiellement exprimés dans les cellules de granulosa de follicules dominants à l’aide de l’hybridation suppressive soustractive (SSH). VIIIième Journée scientifique des programmes de biologie moléculaire. Université de Montréal, Montréal (mai).

Filion F, N Bouchard, J Lussier and J Sirois.  (2001)  Characterization and regulation of prostaglandin E synthase in bovine ovarian cells.  Biol Reprod 64 (Suppl. 1): 159.

Filion, F., Bouchard, N., Goff, A.K., Jakobsson, P-J., Lussier, J. and Sirois, J (2001) Bovine prostaglandin E synthase: molecular cloning and induction in ovarian follicles during the ovulatory process. Biology of Reproduction 64 (Suppl 1) 135

Gagné, D., Robert,C., Bousquet, D., Barnes, F.L., Sirard, MA.(2001) Quantitative evaluation of the mRNA levels of bovine granulosa cell gene markers associated with oocyte developmental competence. Bio Reproduction 64(1) : 481 (résumé)

Gévry N.Y. and Murphy, B.D. 2002 Niemann-Pick C-1 protein in the adrenal. Adrenal 2002: International Adrenal Conference.

Gévry N.Y. and Murphy, B.D. 2002 The Role of sterol regulatory element-binding proteins in the transactivation of Niemann-C1 promoter. Annual Meeting, Endocrine Society, San Francisco.

Gévry, N.Y. Ledoux,S. and Murphy, B.D.  Characterization of ovarian responses and phenotype in mice with mutations in the Niemann-Pick C1 gene. Biol. Reprod. 66 (Suppl 1.):205.

Gévry, N.Y., and Murphy B.D. 2001. Regulation of the Niemann-Pick C1 gene promoter by cyclic AMP-dependent protein kinase A (PKA) and cyclic AMP response element binding protein (CREB). Biol. Reprod. 64(Suppl. 1):264.

Kombé A, J Sirois and AK Goff.  (2002)  The effect of progesterone and estradiol on the sensitivity of endometrial epithelial cells to oxytocin.  Biol. Reprod. 66 (suppl. 1):322.

Lajoie S, J Sirois and M Doré.  (2001)  Expression of cyclooxygenase-2 in naturally-occurring porcine gastric ulcers.  The 2001 Experimental Biology meeting, Orlando, Florida.  FASEB J 15: A823.

Lévesque V, Fayad T, Sirois J Silversides DW, Lussier JG. 2002. Identification de gènes induits par l’hormone lutéinisante (LH) dans les cellules de granulosa de follicules préovulatoires à l’aide de l’hybridation suppressive soustractive (SSH). VIIIième Journée scientifique des programmes de biologie moléculaire. Université de Montréal, Montréal (mai).

Lévesque V, Fayad T, Sirois, J, Silversides DW, Lussier JG. 2001. Génomique fonctionnelle de l’ovulation chez les mammifères. Journée de la recherche des biologistes en reproduction et développement du grand Montréal. Université de Montréal (novembre).

Lévesque V, T Fayad, J Sirois, DW Silversides and JG Lussier. (2001)  Génomique fonctionnelle de l'ovulation chez les mammifères.  Journée de la recherche des biologistes en reproduction et développement du grand Montréal.  Université de Montréal.

Lussier JG, J Sirois, C Price, P Carrière, DW Silversides.  (2001)  Research in genomics applied at the undergraduate level: when research meets teaching objectives. Biol Reprod 64 (Suppl. 1): 134.

Miretti, M., Pereira, H.A., Greggio, C., Suzuki Jr., J., Ferro, J.A., Meirelles, F.V., Garcia, J.M. and Smith, L.C. (2001) The complete mitochondrial genome nucleotide sequence of Bos indicus. International Congress of Genetics, Brazil.

Ndiaye K, Brûlé S, Silversides DW, Lussier JG. 2001. Caractérisation d’une protéine membranaire de 25.3 kDa isolée de cellules de granulosa bovine et démontrant une association aux vésicules périnucléaires. 69ième Congrès de l’Association canadienne française pour lavancement des sciences. Université de Sherbrooke, Sherbrooke, Québec (mai).

Ndjiaye K, S. Brûlé, J. Sirois, D.W. Silverisdes and JG Lussier.  (2001)  Characterization of a new cDNA from a bovine granulosa/oocyte cDNA library coding for a 25.4 kDa integral membrane protein that is associated with perinuclear vesicles. Biol Reprod 64 (Suppl. 1): 157

Paradis V, Lussier JG, Silversides DW. 2001. Cibles potentielles du facteur de transcription SRY : les gènes candidats Vanin-1, Nexin-1 et FGF-9. Journée de la recherche des biologistes en reproduction et développement du grand Montréal. Université de Montréal (novembre).

Parent J, P Chapdelaine, J Arosh, J Sirois and MA Fortier.  (2001)  Characterization of prostaglandin E synthase in bovine endometrium. Biol Reprod 64 (Suppl. 1):321.

Pilon N , Daneau I, Viger R, Behdjani R, Lussier JG, Silversides DW. 2001. In vitro characterization of the pig SRY promotor. 34th Annual meeting of the Society for the Study of Reproduction, Biology of Reproduction 64 Suppl.1 :155 (juillet).

Pontes JHF, Therrien J, Bordignon V et Smith LC (2001) Expression du gène d’interferon-tau par des embryons bovins reconstitué par transfert nucléaire. 9e Rencontre Hivernal Forêt Montmorencys, Québec;

Robert, C., Gagné, D., Bousquet, D., Barnes, F., Sirard, M-A. (2001) Differential display and suppressive subtractive hybridization used to identify granulosa cell Rmessenger RNA associated with bovine oocyte. Biology of Reproduction 64(6) :1812-1820.

Ruiz-Cortés, Z.T., Crosio. C. Sassone-Corsi, P., and Murphy, B.D. 2002. Follicle stimulating hormone, estradiol and leptin stimulate histone H-3 phosphorylation during cyclic differentiation of the ovarian follicle.  Biol. Reprod. 66 (Suppl 1.):102

Ruiz-Cortés, Z.T., Downey, B.R. and Murphy, B.D. 2001. Signaling pathways and local effects of leptin in the porcine ovary. Biol. Reprod. 64(Suppl. 1):131

Sayasith K, N Bouchard, M Sawadago and J Sirois.  (2002)  Transcription regulation of bovine prostaglandin G/H synthase-2 by upstream stimulatory factor (USF) 1 and USF2. Biol. Reprod. 66 (suppl. 1):250-251.

Stock AE, DW Silversides and J Sirois.  (2002)  Establishment and preliminary characterization of immortalized equine granulosa cell lines. Biol. Reprod. 66 (suppl. 1):214.

Therrien J, Bordignon V et Smith LC (2001) Transfection de cellules somatiques bovine pour la production d’animaux transgéniques par clonage. 9e Rencontre Hivernal Forêt Montmorencys, Québec;

Vigneault C, Therrien J et Smith LC (2001) Recherche de région methylé d’une façon differentielle chez des gènes imprégnés bovins. 9e Rencontre Hivernal Forêt Montmorency, Québec;

Wang, B. and Goff, A.K. (2001) Progesterone-modulated induction of apoptosis by interferon-tau in cultured epithelial cells of bovine endometrium. Biology of Reproduction 64 (Suppl 1) 543.

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Libros (2001-2002)

Patentes y genotecas (2001-2002)

Banuelos,R., Nicola,E. and Price,C. (2002) Capra hircus heat shock protein-90 mRNA, partial cds. AF548366 Bédard J, Brûlé S, Price C, Silversides DW, Lussier JG (2002) Bovine granulosa cell SERPINE2, mRNA complete cds. GenBank : AF251153.

Boyer AD, Dornan SC, Daneau I, Lussier JG, Silversides DW (2001) Sus scrofa double-sex and mab-related transcription factor 1 (DMRT1) gene, promoter region. GenBank : AF426435.

Paradis V, Lussier JG, Silversides DW (2001) Sus scrofa nexin-1 (PN-1) mRNA, partial cds. GenBank : AY059415.

Filion F, Bouchard N, Goff AK, Lussier JG, Sirois J (2001) Bos taurus prostaglandin E synthase mRNA, complete cds. GenBank: AY032727.