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LABORATORY OF DR. CARL A. GAGNON
- Research team - Field of activities - Publications -
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Telephone: (450) 773-8521 / office 8681 or laboratory 8603 |
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Fax: (450) 778-8113 |
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E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it. |
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Research Assistant:
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Laboratory Technicians:
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M.Sc Students:
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M.Sc. Student – DVM/M.Sc. Program:
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Postdoctoral Fellows:
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The expertise of Dr Carl A. Gagnon led him to develop a research program focussing on the pathogenesis of the Porcine reproductive and respiratory syndrome virus (PRRSV), responsible for the most important wastes of viral origin in porcine industry. By using classical virology techniques, molecular biology and immunology, combined to international collaborations, Dr Gagnon is working on recombinant vaccines against PRRSV. Also, a close collaboration exists between diagnostic service of the Faculté de médecine vétérinaire of the Université de Montréal. Thus, the various tools developed in his laboratory will be used by this service.
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PUBLICATIONS
2010-2009-2008-2007-2006-2005
C.A. Gagnon, J. Tremblay, D. Larochelle, N. Music and D. Tremblay. 2010. Identification of a novel herpesvirus DNA sequence in cutaneous ulcer lesions found in a sudden death case of a fisher (Martes pennanti) (In redaction).
R. Drolet, F. Cardinal, A. Houde, C.A. Gagnon. 2010. Unusual central nervous system lesions in slaughter-weight pigs with porcine circovirus type 2 systemic infection. Can Vet J (Accepted for publication).
C.A. Gagnon, O. Allam, R. Drolet, D. Tremblay. 2010. Detection of bovine lymphotropic herpesvirus DNA in tissues of a bovine aborted fetus in Québec. Can Vet J (Accepted for publication).
N. Music, C.A. Gagnon. 2010. The role of porcine reproductive and respiratory syndrome virus (PRRSV) structural and non-structural proteins in virus pathogenesis. Animal Health Res Reviews (In press).
F.R. Okamba, M. Arella, N. Music, J.J. Jia, M. Gottschalk, C.A. Gagnon. 2010. Potential use of a recombinant replication-defective adenovirus vector carrying the C-terminal portion of the P97 adhesin protein as a vaccine against Mycoplasma hyopneumoniae in swine. Vaccine 28(30):4802-4809.
C.A. Gagnon, N. Music, G. Fontaine, D. Tremblay, J. Harel. 2010. Emergence of a new type of porcine circovirus (PCV) in swine: a type 1 and type 2 PCV recombinant. Vet Microbiol 144:18-23.
D.W. Silversides, N. Music, M. Jacques, C.A. Gagnon, R. Webby. 2010. Investigation of the species origin of the St. Jude porcine lung epithelial cell line (SJPL) made available to researchers. J. Virol. 84(10):5454-5455.
D. Verreault, V. Létourneau. L. Gendron, D. Massé, C.A. Gagnon, C. Duchaine. 2010. Airborne porcine circovirus in Canadian swine confinement buildings. Vet Microbiol 141:224-230.
C.A. Gagnon, G. Spearman, A. Hamel, D.L. Godson, A. Fortin, G. Fontaine, D. Tremblay. 2009. Characterization of a Canadian mink H3N2 influenza A virus isolate genetically related to triple reassortant swine influenza virus. J Clin Microbiol 47:796-799.
C.A. Gagnon et J.P. Vaillancourt. 2009. H1N1: État de situation au Québec et au Canada. Le Veterinarius FLASH de l’Ordre des médecins vétérinaires du Québec.
F. R. Okamba, M. Arella, N. Music, J.J. Jia, B. Massie, C.A. Gagnon. 2009. Protection induced by a recombinant replication-defective adenovirus vaccine expressing the P97 protein of Mycoplasma hyopneumoniae in challenged pigs: Comparison to Suvaxyn MH-one vaccine. Proceedings of the 40th Annual meeting of the American Association of Swine Veterinarians (AASV). Dallas, Texas, USA. Du 7 au 10 mars. Page 117-124.
L. Batista, M.A. Paradis, C.A. Gagnon, M. Gottschalk. 2009. Evaluation of the effects of tilmicosin (Pulmotil AC®) administered in drinking water on nursery pigs inoculated with porcine reproductive and respiratory syndrome virus. Proceedings of the 40th Annual meeting of the American Association of Swine Veterinarians (AASV). Dallas, Texas, USA. Du 7 au 10 mars. Page 173-177.
C.A. Gagnon, J. del Castillo, N. Music, G. Fontaine, J. Harel, D. Tremblay. 2008. Development and use of a multiplex real-time quantitative polymerase chain reaction assay for detection and differentiation of Porcine circovirus-2 genotypes 2a and 2b in an epidemiological survey. J Vet Diagn Invest, 20:545-558.
S. Carman, H. Cai, J. DeLay, Sameh Y.B. McEwen, C.A. Gagnon, D. Tremblay, M. Hazlett, P. Lusis, J. Fairles, H. Alexander and T. van Dreumel. 2008. The emergence of a new strain of porcine circovirus-2 with PCR restriction fragment length polymorphism type 321 in Ontario and Quebec swine and its association with severe porcine circovirus associated disease – 2004-2006. Can J Vet Res 72:259-268.
C.A. Gagnon. 2008. Mise en évidence et analyse génomique d’un virus influenza H3N2 apparu dans la population de vison suite à l’ingestion de produits carnés provenant d’abattoir de porc. Info CRIP. Décembre 2008, page 5-6.
C.A. Gagnon, S. M. Elahi, D. Tremblay, N. A. Bryant, D. M. Elton, J.-P. Lavoie, S. Carman and J. Elsener. 2007. Cross Canada Disease Report - Genetic relatedness of recent Canadian equine influenza virus isolates with vaccine strains used in the field. Can. Vet. J. 48(10):1028-1030.
C.A. Gagnon. 2007. Qu’est-ce que le virus influenza? Méd. Vét. Québec. 36(2):64-68.
C.A. Gagnon. 2007. Les méthodes de diagnostic employées au Québec pour la détection du virus influenza aviaire. Méd. Vét. Québec. 36(2):74-78.
C.A. Gagnon, D. Tremblay, P. Tijssen, M.-H. Venne, A. Houde and S.M. Elahi. 2007. The emergence of porcine circovirus 2b genotype (PCV-2b) in swine in Canada. Can. Vet. J. 48(8):811-819.
F.R. Okamba, E. Moreau, K. Cheikh Saad Bouh, C.A. Gagnon, B. Massie, and M. Arella. 2007. Immune responses induced by replication-defective adenovirus expressing the C-terminal portion of the Mycoplasma hyopneumoniae P97 adhesin. Clin. Vaccine Immunol. 14(6):767-774.
C.A. Gagnon, D. Tremblay. 2007. Où en sommes-nous avec le circovirus porcin de type 2? InfoSD, Bulletin du service de diagnostic de la Faculté de médecine vétérinaire de l’U de Mtl. Août 2007, volume 1, numéro 1, page 3.
C. A. Gagnon, D. Tremblay, P. Tijssen, M.-H. Venne, A. Houde, S. M. Elahi. 2007. PCV2 strain variation: What does it mean? Proceedings of the 38th Annual meeting of the American Association of Swine Veterinarians (AASV). Orlando, Floride, USA. Du 3 au 6 mars. Page 535-540.
Gagnon, C.A. 2007. Le circovirus et le syndrome de dépérissement en post-sevrage. Le Québec rural & agricole: Avril/mai 2007; volume 3, numéro 3.
Ellis, J.A., J. Harding J, C. Gagnon, A. Hamel. 2006. Porcine circovirus disease in Canada : A circle within a wheel. In : PCVD: Coming full circle. Editor : Merial. 23-34.
D’Allaire, S., L. Batista and C.A. Gagnon. 2005. Nouveau programme de recherche sur l’épidémiologie et le contrôle du syndrome reproducteur et respiratoire porcin (SRRP) au Québec. InfoGREMIP/Newsletter–Été 2005, Numéro 4, 2 pages.
Kheyar, A. Jabrane, C. Zhu, P. Cléroux, B. Massie, S. Dea and C.A. Gagnon. 2005. Alernative codon usage of PRRS virus ORF5 gene increases eukaryotic expression of GP5 glycoprotein and improves immune response in challenged pigs. Vaccine 23:4016-4022.