Groupe de recherche en pharmacologie animale du Québec (GREPAQ)

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Revue de presse et médias

Les souffrances secrètes des animaux Article publié dans le quotidien de Québec Le Soleil du 30 juin 2013. Faculté de médecine vétérinaire – Université de Montréal / St-Hyacinthe (QC, Canada).

Manifestation de la douleur chez le chat atteint d'ostéoarthrite À la suite de la parution d’études du GRÉPAQ dans Research in Veterinary Science le 13 février 2013 (Moreau M, et al., Kinetic peak vertical force measurement in cats afflicted by coxarthritis: Data management and acquisition protocols) et dans le Veterinary Journal le 14 février 2013 (Guillot M, et al. Characterization of osteoarthritis in cats and meloxicam efficacy using objective chronic pain evaluation tools), ces publications ont été cités dans de nombreux journaux auxquels vous pouvez accéder grâce aux liens ci-dessous :

En français En anglais

La nourriture pour chats Interview télévisé pour  L’épicerie - Radio Canada. Diffusé le 24 novembre 2010. Faculté de médecine vétérinaire – Université de Montréal / St-Hyacinthe (QC, Canada).

Devenir chercheur vétérinaire Interview télévisé pour  Le Code Chastenay  – Télé Québec. Diffusé le 8 décembre 2008. Faculté de médecine vétérinaire – Université de Montréal / St-Hyacinthe (QC, Canada).

Un mal de chien Interview télévisée pour Vidéos sur demande – Canal Savoir.tv Diffusé le 9 décembre 2008. Faculté de médecine vétérinaire – Université de Montréal / St-Hyacinthe (QC, Canada).

Activités

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Publications 2010-     (étudiants soulignés)

Articles

Steagall, P.V.; Monteiro-Steagall, B.P.; Lavoie, A.M.; Frank, D.; Troncy, E.; Luna, S.P.; Brondani, J.T. – Validation of the French version of the UNESP-Botucatu multidimensional composite pain scale for assessing postoperative pain in cats – Validation de la version francophone d’une échelle composite multidimensionnelle pour l’évaluation de la douleur postopératoire chez les chats. Canadian Veterinary Journal – Journal Vétérinaire Canadien. 58(1):56-64, Jan 2017.

Annexe: Échelle de douleur composite multidimensionnelle UNESP-Botucatu

Résumé

L’objectif de cette étude était de valider la version francophone de l’échelle composite multidimensionnelle de douleur UNESP-Botucatu (MCPS-Fr) chez les chats. Deux vétérinaires et une étudiante de médecine vétérinaire francophones ont identifié trois catégories de comportements distincts sur des vidéos : «les changements psychomoteurs», «la protection de la région douloureuse» et «les variables physiologiques». La cohérence interne était excellente (score total du coefficient alpha de Cronbach était de 0,94; 0,90; et 0,61, respectivement). La bonne concordance entre les évaluations à l’aveugle des observateurs et l’évaluateur de référence confirme la validité de cet instrument. La fiabilité inter- et intra-évaluateur était bonne à très bonne. Le point limite optimal pour l’analgésie de secours, identifié avec une courbe ROC, était au-delà de 7 (échelle allant de 0 à 30 points), avec une sensibilité de 97,8 % et une spécificité de 99,1 %. La MCPS-Fr est un outil valide et sensible pour l’évaluation de la douleur aiguë chez les chattes ayant subi une ovariohystérectomie.

Abstract

Validation of the French version of the UNESP-Botucatu multidimensional composite pain scale for assessing postoperative pain in cats. The aim of this study was to validate the French version of the UNESP-Botucatu multidimensional composite pain scale (MCPS-Fr) to assess postoperative pain in cats. Two veterinarians and one DVM student identified three domains of behavior based on video analyses: “psychomotor change”, “protection of the painful area” and “physiological variables”. Internal consistency was excellent (Cronbach’s alpha coefficient of 0.94, 0.90 and 0.61, respectively). Criterion validity was good to very good when evaluations from the three observers were compared with a “gold standard”. Inter- and intra-rater reliability for each scale item were good to very good. The optimal cut-off point identified with a ROC curve was > 7 (scale range 0–30 points), with a sensitivity of 97.8% and specificity of 99.1%. The MCPS-Fr is a valid, reliable and responsive instrument for assessing acute pain in cats undergoing ovariohysterectomy.

(Translated by Dr. Beatriz Monteiro)

Pailleux, F., Lemoine, J., Beaudry, F. Investigation of the Metabolic Biotransformation of Substance P in Liver Microsomes by Liquid Chromatography Quadrupole Ion Trap Mass Spectrometry, Biomedical Chromatography, Manuscript ID: BMC-12-0050, Accepted. (2012)

Robert, V.L., Beaudry, F and Vachon, P. Evaluation of physiological changes in Xenopus laevis frogs and pharmacological parameters of MS-222 following an immersion bath at anesthetic doses, Journal of the American Association for Laboratory Animal Science, manuscript ID: JAALAS-11-000161. Accepted (2012)

Ferland, C.E., Beaudry, F and Vachon, P. Antinociceptive effects of eugenol in a monoiodoacetate-induced osteoarthritis rat model. Phytotherapy Research, Manuscript ID : PTR-11-0779. Available online (2012)

Bermingham, E., del Castillo,  J.R.E., Lainesse, C., Pasloske, K. and Radecki, S. (2011). Demonstrating bioequivalence using clinical endpoint studies. J Vet Pharmacol Ther (accepted, manuscript # JVPT-2011-).

Hewson, J., Johnson, R., Arroyo, L.G., Diaz-Mendez, A., Ruiz-Lopez, J.A., Gu, Y. and del Castillo, J.R.E.  Comparison of continuous infusion with intermittent bolus administration of cefotaxime on blood and cavity fluid drug concentrations in neonatal foals. J Vet Pharmacol Ther (accepted, manuscript # JVPT-2011-1250). (2011).

Chorfi, Y., Girard, V., Fournier, A., Couture, Y. Effect of subcutaneous selenium injection and supplementary selenium source on blood selenium and glutathione peroxidase in feedlot heifers. Canadian Veterinary Journal. 52: 10, 1089 (2011) accepted

Rialland, P., Bichot, S., Lussier, B., Moreau, M., Beaudry, F., del Castillo, J.R.E., Gauvin, D. and Troncy E. Effect of a green-lipped mussel-enriched diet on pain behaviours and functioning in dogs with clinical osteoarthritis. Can J Vet Res (submitted, manuscript # 2011-0094) (2011).

Moreau, M., Troncy, E., del Castillo, J.R.E., Bédard, C., Gauvin, D. and Lussier, B. (2011). Effects of feeding a high omega-3 fatty acid diet on the pain-related disability in dogs with naturally occurring osteoarthritis. J Anim Physiol Anim Nutrition (submitted,  manuscript # JAPAN-Jan-12-038)

Pailleux, F. and Beaudry, F. Deletion of the TRPV1 receptor in mice alters substance P and neurokinin A expression in the central nervous system, Molecular Pain. Submitted. (2011)

Robert, V.L., Beaudry, F., and Vachon, P. Evaluation of physiological changes in Xenopus laevis frogs and pharmacological parameters of MS-222 following an immersion bath at anesthetic doses. Journal of the American Association for Laboratory Animal Science, manuscript ID: JAALAS-11-000161. Submitted  November 2011.

Richards, J.S., Fan, H.Y., Liu, Z., Tsoi, M., Laguë, M.N., Boyer, A. and Boerboom, D. Either Kras activation or Pten loss similarly enhance the dominant-stable CTNNB1-induced genetic program to promote granulosa cell tumor development in ovary and testis. Oncogene In press (2012).

Deschesne, K., Céleste, C., Boerboom, D. and Theoret, C.L. Hypoxia regulates the expression of extracellular matrix associated proteins in equine dermal fibroblasts via HIF1. Journal of Dermatological Science. In press (2012).

Ferland, C.E., Beaudry, F. and Vachon, P. Antinociceptive effects of eugenol in a monoiodoacetate-induced osteoarthritis rat model. Phytotherapy Research, Manuscript accepted. PTR-11-0779, In press (2011)

Bao, K.D., Letellier, A. and Beaudry, F.Analysis of Staphylococcus Enterotoxin B using Differential Isotopic Tags and Liquid Chromatography Quadrupole Ion Trap Mass Spectrometry. Biomedical Chromatography. Oct; doi: 10.1002/bmc.1742, Available on line, In press (2011)

Gauthier, M.-L., Douat, J., Vachon, P. and Beaudry, F. Characterization of [6]-Gingerol Metabolism in Rat by Liquid Chromatography Electrospray Tandem Mass Spectrometry, Biomedical Chromatography. Oct; 25(10):1150-1158 (2011).

Ferland, C.E., Pailleux, F., Vachon, P. and Beaudry, F. Determination of specific neuropeptides modulation time course in a rat model of osteoarthritis pain by liquid chromatography ion trap mass spectrometry, Neuropeptides. Oct; 45(6):423-429 (2011).

Guillot, M., Rialland, P., Nadeau, M.-E., del Castillo, J.R.E., Gauvin, D., Troncy, E. – Pain induced by a minor medical procedure (bone marrow aspiration) in dogs: Comparison of pain scales in a pilot study. Journal of Veterinary Internal Medicine. Sep-Oct ;25:1050-1056 (2011).

Pinard, C.L., Gauvin, D., Moreau, M., Martel-Pelletier, J., Pelletier, J.-P., Troncy, E. – Measurement of canine aqueous humor inflammatory mediators and the effect of carprofen following anterior chamber paracentesis. Veterinary Ophthalmology. Sep;14(5):296-303 (2011).

Paquet, M., El-Warrak, A.O., Laguë, M.N. and Boerboom, D. Atypical caudal duplication with pseudohermaphroditism in a dog. Journal of Veterinary Diagnostic Investigation. Sep;23(5):1037-40(2011).

Guillot, M., Alexander, K., Pomar, C. and del Castillo,  J.R.E. Dietary chlortetracycline induces differential effects on the accuracy of quantitative computed tomography and dual energy X-ray absorptiometry in assessing vertebral bone mineral density in growing pigs. Veterinary Journal. Aug;  185: 169-173 (2010).

Alexander, K., Dunn, M., Carmel, E.-N., Lavoie,  J.P., del Castillo, J.R.E. Clinical application of Patlak plot CT-GFR in animals with upper urinary tract disease. Vet Radiol Ultrasound. Jul-Aug; 51: 421-7 (2010).

Authier, S., Gervais, J., Fournier, S., Gauvin, D., Maghezzi, S., Troncy, E. – Cardiovascular and respiratory safety pharmacology in Göttingen minipigs: Pharmacological characterization. Journal of Pharmacological and Toxicological Methods.  Jul-Aug; 64(1):53-59 (2011).

Boerboom, D., Lafond, J.F., Zheng, X., Lapointe, E., Mittaz, L., Boyer, A., Pritchard, M.A., DeMayo, F.J., Mort, J.S, Drolet, R. and Richards, J.S. Partially redundant functions of Adamts1 and Adamts4 in the perinatal development of the renal medulla. Developmental Dynamics.  Jul;240(7):1806-14 (2011).

Guillot, M., Alexander, K., Pomar, C. and del Castillo,  J.R.E. In growing pigs, chlortetracycline induces a reversible green bone discoloration and persistent increase of bone mineral density dependent of dosing regimen. Research in Veterinary Science. Jun; 90: 484-90 (2011).

Moreau, M., Rialland, P., Pelletier, J.-P., Martel-Pelletier, J., Lajeunesse, D., Boileau, C., Caron, J., Frank, D., Lussier, B., del Castillo, J.R.E., Beauchamp, G., Gauvin, D., Bertaim, T., Thibaud, D.and Troncy, E. – Tiludronate treatment improves structural changes and symptoms of osteoarthritis in the canine anterior cruciate ligament model. Arthritis Research & Therapy. 13(3):R98, Jun 21 (2011).
An editorial highlights the importance and the quality of this publication: Walsh and Chapman Arthritis Research & Therapy 2011, 13:128
http://arthritis-research.com/content/13/5/128

Authier, S., Moon, L.B., Stonerook, M., Fournier, S., Gervais, J., Maghezzi, S., Troncy, E. – Evaluation of a novel ECG lead placement method in telemetered freely moving cynomolgus monkeys: Assessment of an intravenous biopotential lead. Journal of Pharmacological and Toxicological Methods. DOI: 10.1016/j.vascn.2011.05.007. Published online Ahead of Print, Jun 2011.

Franco, H.L., Dai, D., Lee, K.Y., Rubel, C.A., Roop, D., Tsai, S.Y., Boerboom, D., Lydon, J.P., Jeong, J.W., Bagchi, I.C., Bagchi, M.K. and DeMayo, F.J. WNT4 is a key regulator of proper postnatal uterine development and progesterone signaling during embryo implantation and decidualization. The FASEB Journal. Apr;25(4):1176-87 (2011).

Douat, J., Vachon, P. and Beaudry, F. In Vitro Metabolism of Capsazepine, a Vanilloid Transient Receptor Potential  Channel Antagonist, by Liquid Chromatography Quadrupole Ion Trap Mass Spectrometry, Biomedical Chromatography. Apr; 25(4):479-492 (2011).

Deschesne, K., Céleste, C., Boerboom, D. and Theoret, C.L. Constitutive expression of HIF-1α in keratinocytes during the repair of skin wounds in horses. Wound Repair and Regeneration. Mar;19(2):250-9 (2011).

Ferland, C.E., Laverty, S., Beaudry, F. and Vachon, P. Gait Analysis and Pain Response of Two Rodent Models of Osteoarthritis. Pharmacology Biochemistry and Behavior. Jan;97(3):603-610 (2011).

Lapointe, E. and Boerboom, D. WNT signaling and the regulation of ovarian steroidogenesis. Frontiers in Bioscience. Jan;S3(1):276-85 (2011).

Pelletier, J.-P., Troncy, E., Goulet, A.-C., Abram, F., Caron, J., Boileau, C., d’Anjou, M.-A., Moreau, M., Lussier, B., Martel-Pelletier, J. – Treatment with tiludronic acid helps reduce the development of experimental osteoarthritis lesions in dogs with anterior cruciate ligament transection followed by reconstructive surgery: A 1-year study with quantitative magnetic resonance imaging. Journal of Rheumatology. Jan; 38(1):118-128 (2011).

Ybarra, N., del Castillo, J.R.E. and Troncy, E. – Involvement of the nitric oxide – soluble guanylyl cyclase pathway in the oxytocin-mediated differentiation of porcine bone marrow stem cells into cardiomyocytes. Nitric Oxide: Biology and Chemistry. Jan; 24(1):25-33 (2011).

Beaudry, F. Stability comparison between sample preparation procedures for mass spectrometry-based targeted or shotgun peptidomic analysis, Analytical Biochemistry. Dec;407:290-292 (2010).

Laguë, M.N., Detmar, J., Paquet, M., Boyer, A., Richards, J.S., Adamson, S.L. and Boerboom, D. Decidual PTEN expression is required for trophoblast invasion in the mouse. American Journal of Physiology: Endocrinology & Metabolism. Dec;299(6):E936-46 (2010).

Legaspi, M., Authier, S., Gauvin, D., Moreau, M., Chaurand, F., Troncy, E. – Respiratory safety pharmacology: Concurrent validation of volume, rate, time, flow and ratio variables in conscious male Sprague-Dawley rats. Regulatory Toxicology and Pharmacology. Dec;58(3) :444-450 (2010).

Lionnet, L., Beaudry, F. and P. Vachon. Intrathecal eugenol administration alleviates neuropathic pain in male Sprague-Dawley rats, Phytotherapy Research. Nov; 24:1645-1653 (2010)

Brown, H.M., Dunning, K.R., Robker, R.L., Boerboom, D., Pritchard, M., Lane, M., and Russell, D.L. Adamts1 cleavage of versican mediates essential structural remodelling of the ovarian follicle and cumulus-oocyte matrix during ovulation. Biology of Reproduction. Oct;83(4):549-57 (2010).

Authier, S., Pugsley, M.K., Troncy, E. and Curtis, M.J. – Arrhythmogenic liability screening in cardiovascular safety pharmacology: Commonality between non-clinical safety pharmacology and clinical Thorough QT (TQT) studies. Journal of Pharmacological and Toxicological Methods. Sep – Oct; 62(2):83-88 (2010).

Duhamel, M.C., Troncy, E. and Beaudry, F. Metabolic Stability and Determination of Cytochrome P450 Isoenzymes Contribution to the Metabolism of Medetomidine in Dog Liver Microsomes, Biomedical Chromatography, Aug;24(8) :868-877 (2010).

Boyer, A., Lapointe, E., Zheng, X., Cowan, R.G., Paquet, M., Quirk, S.M., DeMayo, F.J., Richards, J.S., and Boerboom, D. WNT4 is required for normal ovarian follicle development and female fertility. The FASEB Journal Aug;24(8):3010-25(2010).

Authier, S., Haefner, P., Fournier, S., Troncy, E. and Moon, L.B. – Combined cardiopulmonary assessments with implantable telemetry device in conscious freely moving cynomolgus monkeys. Journal of Pharmacological and Toxicological Methods. , Jul -Aug; 62(1):6-11, (2010).

Boileau, C., Martel-Pelletier, J., Caron, J., Paré, F., Troncy, E., Moreau, M. and Pelletier, J.-P. – Oral treatment with a Brachystemma calicinum D. Don plant extract reduces the development of cartilage lesions in experimental dog osteoarthritis: Inhibition of protease activated receptor-2 (PAR-2). Annals of the Rheumatic Diseases. Jun; 69(6):1179-1184 (2010).

Buczinski, S., Rezakhani, A. and Boerboom, D. Heart disease in cattle: a review of the current data regarding diagnosis, therapeutic approaches and prognosis. The Veterinary Journal. Jun;184(3):258-63 (2010).

Alexander, K., Authier, S., del Castillo, J.R.E., Arora, V., Qi, S., Guillot, M., Beauchamp, G.and Troncy, E. – Patlak plot analysis CT-GFR for the determination of renal function: Comparison of normal dogs with autologous kidney transplant dogs. Contrast Media and Molecular Imaging. May; 5(3):133-139 (2010).

Beaudry, F., Ross, A., Lema, P.P. and Vachon, P. Pharmacokinetics of vanillin and its effects on mechanical hypersensitivity in rat model of neuropathic pain. Phytotherapy Research. Apr; 24(4):525-530 (2010).

Kaartinen, J., Pang, D.S.J., Moreau, M., Vainio, O., Beaudry, F., del Castillo, J.R.E., Lamont, L., Cuvelliez, S., Troncy, E. – Hemodynamic effects of an intravenous infusion of medetomidine at six different dose regimens in isoflurane-anesthetized dogs. Veterinary Therapeutics. Spring;11(1):E1-E16 (2010).

Boyer, A., Goff, A.K. and Boerboom, D. WNT signaling in ovarian follicle biology and tumorigenesis. Trends in Endocrinology and Metabolism. Jan;21(1):25-32 (2010).

Authier, S., Tanguay, J.-F., Geoffroy, P., Gauvin, D., Bichot, S., Ybarra, N., Otis, C. and Troncy, E. – Cardiovascular effects of oxytocin infusion in a porcine model of myocardial infarct. Journal of Cardiovascular Pharmacology. Jan;55(1):74-82 (2010).

Moreau, M., Troncy, E., Bichot, S., Lussier, B. – Influence of changes in body weight on peak vertical force in osteoarthritic dogs. A possible bias in study outcome. Veterinary Surgery. Jan; 39(1):43-47 (2010).

Dupras, R., Dupras, J., Chorfi, Y. Estradiol-17β concentrations in blood and milk during superovulatory treatment in dairy cows. Reproduction, Fertility and Development. Jan; 22 (1): 245-245 (2010).

Livres / Chapitres de livres

Troncy, E. – Veterinary sciences at the center of the animal welfare debate. [French]. In: Lachance, M. Premier colloque international en droit animal au Canada – L’animal dans la spirale des besoins de l’humain. Editions Yvon Blais – Thomson Reuters Canada Ltd., Cowansville (QC, Canada) March 2010: 223-242, ISBN 978-2-89635-490-0.

Authier, S.; Pugsley, M.K.; Troncy, E.; Curtis, M.J. – Cardiovascular biomarkers as examples of success and failure in predicting safety in humans. In: Williams, J.A.; Koup, J.R.; Lalonde, R.; and Christ, D.D. [Eds], Predictive Approaches in Drug Discovery and Development: Biomarkers and In Vitro/In Vivo Correlations. John Wiley & Sons, Inc. Hoboken, NJ, USA, 2012: 163-188.

Présentations scientifiques

59th Annual American Society for Mass Spectrometry Conference, Colorado  (USA) Gauthier, M.L., Douat, J., Vachon, P., and Beaudry, F. (2011), Characterization of [6]-Gingerol Metabolism in Rat by LC-MS/MS and Accurate-Mass TOF (USA), JASMS, 22(S1), WP.278F. Pailleux and F. Beaudry (2011), Comparison of neuropeptides stability using different preparation protocols for mass spectrometry-based targeted peptidomic analysis. JASMS, 22(S1), MP.508

51st Annual Meeting of the Society of Toxicology, March 11-15, 2012, Moscone Convention Center / San Diego (California, United States of America).
Poster – Discussion: Respiratory safety pharmacology in rats, canines and non-human primates: Comparison of minimal detectable difference. Authier, S.; Forster, R.; Ascah, A.; Pouliot, M.; Troncy, E.
Oral presentation: Acute radiation syndrome: Hematopoietic characterization of a non-rodent model. Duguay, F.; Pouliot, M.; Ascah, A.; Forster, R.; Troncy, E.; Authier, S.
Poster – Discussion: Safety pharmacology in the Göttinger minipigs: Cardiovascular, respiratory and neurological investigations. Mikaelian, R.; Authier, S.; Fournier, S.; Pouliot, M.; Ascah, A.; Troncy, E.; Forster, R.
Poster – Discussion: Arousal and spectral analysis: EEG in conscious Cynomolgus monkeys. Fournier, S.; Maghezzi, S.; Schaeffer, E.; Weed, M.; Digavalli, S.; Troncy, E.; Forster, R.; Authier, S.
Poster – Discussion: Functional observation battery in non-human primates with continuous intracerebral infusion. Aslam, A.S.; Authier, S.; Schneider, A.; Wong, K.; Bienvenu, J.-G.; Tavcar, R.; Forster, R.; Troncy, E.
Poster – Discussion: QT correction methods: Can we further optimize methods in Cynomolgus monkeys, Beagle dogs and Göttingen minipigs. Stein, A.; Authier, S.; Ascah, A.; Pouliot, M.; Forster, R.; Troncy, E.

92nd Annual Meeting of the Conference of Research Workers in Animal Diseases (CRWAD). December 4-6, 2011, Chicago (Illinois, U.S.A.).
Présentation orale: Effect of deoxynivalenol (DON) mycotoxin on porcine reproductive respiratory syndrome virus (PRRSV) in vitro., C. Savard*, V. Pinilla, C. Provost,  M. Segura, C.A. Gagnon, Y. Chorfi.

International porcine reproductive and respiratory syndrome symposium 2011. December 2-3, 2011, Chicago (Illinois, U.S.A.).
Poster: Effect of deoxynivalenol (DON) mycotoxin on porcine reproductive respiratory syndrome virus (PRRSV) in vitro. V. Pinilla, C. Savard*, C. Provost, M. Segura, C.A. Gagnon, Y. Chorfi.

Annual congress of the American College of Veterinary Surgeons November 03 – 05, 2011, Hyatt Regency Hotel / Chicago (Illinois, U.S.A.).
Oral Presentation: Efficacy of a Chinese plant extract (Brachystemma calycinum D don) on the pain-related disability in dogs with naturally occurring osteoarthritis. Moreau, M.; Lussier, B.; Pelletier, J.-P.; Gauvin, D.; Martel-Pelletier, J.; Troncy, E. Veterinary Surgery, 40:E36, Nov 2011.

62nd AALAS National Meeting (October 2-6, 2011), San Diego, California (USA).
Oral presentation: Veilleux-Lemieux, D., Beaudry, F. and Vachon, P. (2011), Effects of Lipopolysaccharide on Physiologic and Pharmacological Parameters Following Ketamine-Xylazine Administration at an Anesthetic Dose in Rat, JOURNAL OF THE AMERICAN ASSOCIATION FOR LABORATORY ANIMAL SCIENCE, 50(5);  793-794. (2011)

Association des vétérinaires en industrie animale (AVIA) octobre 2011.
Présentation orale: Le diagnostique des problèmes métaboliques et nutritionnels grâce à la biochimie clinique. Chorfi Y ., Venne D.

11th Annual Meeting of the Safety Pharmacology Society, September 19-22, 2011, Congress & Messee Innsbruck / Innsbruck (Austria).
Poster: Functional observation battery in non-human primates with continuous intracerebral infusion. Authier, S.; Schneider, A.; Wong, K.; Bienvenu, J.-G.; Tavcar, R.; Fournier, S.; Troncy, E.
Poster: Super-intervals: Application to respiratory safety pharmacology data in rats. Authier, S.; Some, M.; Fournier, S.; Troncy, E.
Poster: Arousal and spectral analysis: EEG in conscious cynomolgus monkeys. Schaeffer, E.; Weed, M.; Digavalli, S.; Fournier, S.; Maghezzi, S.; Gervais, J.; Troncy, E.; Authier, S.

14th International Congress of Radiation Research Polish Radiation Research Society August 28 – September 01, 2011, The Palace of Culture and Science / Warsaw (Poland).
Poster: Microbiological characterization: Acute radiation syndrome in a Rhesus model. Authier, S.; Gervais, J.; Troncy, E.

Joint ACVB/AVSAB Scientific meeting, July 15, 2011, America’s Center / St.-Louis (Missouri, United States of America).
Oral presentation: Validation and reliability testing of a feline osteoarthritis pain scale for use by veterinarians. Klinck, M.P.; Frank, D.; Guillot, M.; Rialland, P.; Troncy, E.

Colloque de microbiologie animale. Avril 2011
Poster : Facteurs influençant la réponse immunitaire après vaccination contre la maladie de Gumboro chez le poulet de chair. Ramahefarisoa R., Venne D., Frenette D.,  Silim a., Chorfi Y.

58th Annual American Society for Mass Spectrometry Conference (2010), Salt Lake City, (USA).
Poster: Identification, Characterization and Quantification of Neuropeptides by HPLC-ESI/MS/MS in Rat Models of Osteoarthritis. Ferland, C.E., Vachon, P., Beaudry, F. JASMS, 21(5S) MP.188

Café du Centre de Recherche en Infectiologie Porcine (CRIP), 10 Décembre 2010, St-Hyacinthe (Québec, Canada)
Présentation orale: Détection des mycotoxines (DON, OTA) dans les fluides biologiques du porc. Chorfi Y.

15th annual Canine and Feline Cognition, Aging & Neuropathology Conference, November 11-12, 2010, Surf & Sand Resort / Laguna Beach (California, United States of America).
Oral presentation: Characterization of pain in osteoarthritic cats. Troncy, E.

34e Symposium sur les Bovins Laitiers du CRAAQ, 28 octobre 2010, Drummondville, (Québec, Canada).
Poster : Analyses de la vomitoxine (DON) et de l’ochratoxine A (OTA) dans le sérum et l’urine des vaches laitières. Gendron, M-C., Brassard, H., Chorfi, Y.

61st American Association for Laboratory Animal Science Annual Meeting, October 10-14, 2010, Congress Center / Atlanta (Georgia, United States of America).
Poster: Effect of serial blood sampling on hematology parameters in cynomolgus monkeys (Macaca fascicularis). Maghezzi, M.S.; Chaurand, F.; Gervais, J.; Troncy, E.; Authier, S. Journal of the American Association for Laboratory Animal Science, 49(5):684, Nov 2010.
Oral presentation: An innovative surgical technique for telemetry electrocardiogram leads placement in Cynomolgus monkeys (Macaca fascicularis). Chaurand, F.; Stonerook, M.; Moon, B.; Maghezzi, M.S.; Gervais, J.; Troncy, E.; Authier, S. Journal of the American Association for Laboratory Animal Science, 49(5):664-665, Nov 2010.

13th World Congress on Pain of the International Association for the Study of Pain (IASP) – Official Satellite Symposium organised by the Pain and pain management in non-human species Special Interest Group of IASP, August 29-September 02, 2010, Palais des Congrès / Montréal (Quebec, Canada).
Poster presentation: Objective evaluation of osteoarthritis associated-pain in cats: A preliminary study. Guillot, M.; Moreau, M.; d’Anjou, M.-A.; Martel-Pelletier, J.; Pelletier, J.-P.; Troncy, E.

2010 OARSI World Congress on Osteoarthritis, September 23-26, 2010 Square Brussels Meeting Center / Brussels (Belgium).
Oral presentation: Effects of feeding a high omega-3 fatty acid diet on the pain-related disability in dogs with naturally occurring osteoarthritis. Moreau, M.; Troncy, E.; Gauvin, D.; Lussier B. Osteoarthritis and Cartilage. 18(Suppl.2):S23, Oct 2010.

10th Annual Meeting of the Safety Pharmacology Society, September 20-23, 2010, Seaport World Trade Center / Boston (Massachusetts, United States of America).
Poster: Computerized arrhythmia detection in large telemetered animals: Evaluation of canine, primate and porcine ECG data. Authier, S. Koeppel, F.; Rossi, F.; Labarre, D.; Fournier, S.; Troncy, E. Journal of Pharmacological and Toxicological Methods. 64(1):e43, Jul-Aug 2011. doi:10.1016/j.vascn.2011.03.150.
Oral presentation: An innovative surgical technique for telemetry ECG lead placement in Cynomolgus monkeys (Macaca fascicularis). Authier, S.; Stonerook, M.; Troncy, E.; Fournier, S.; Moon, B. Journal of Pharmacological and Toxicological Methods. 64(1):e45, Jul-Aug 2011. doi:10.1016/j.vascn.2011.03.158.
Poster: Strategies to improve sensitivity of respiratory safety pharmacology studies in Cynomolgus monkeys using impedance monitored by implantable telemetry. Authier, S.; Fournier, S.; Troncy, E.; Moon, B. Journal of Pharmacological and Toxicological Methods. 64(1):e56, Jul-Aug 2011. doi:10.1016/j.vascn.2011.03.193.

Joint ACVB (American College of Veterinary Behaviorists)/ ASVAB (American Veterinary Society of Animal Behavior) Scientific meeting, July 30, 2010, Marriott Metro Center / Atlanta (Georgia, United States of America).
Oral presentation: Psychometric validation of pain and quality of life questionnaires in osteoarthritic cats. Klinck, M.P.; Rialland, P.; Guillot, M.; Moreau, M.; del Castillo, J.R.E.; Frank, D.; Troncy, E.

21thInternational Pig Veterinary Society (IPVS) Congress. July 18-21, 2010, Vancouver (Bristish Columbia, Canada). Béraud R, Huneault LM, Bernier D, Beaudry F, Letellier A, del Castillo JRE. Changes in antimicrobial sensitivity of fecal E. coli in pigs exposed to enrofloxacin by different dosing routes: evidence for the “Mutant Selection Window”.
Poster : Comparaison of temporal variation of blood parameters between PRSS naive " 5 kg " gilts and PRRS virus infected resident piglet population commingled in a nursery. Caron, A, Klopfenstein, C, Denicourt, M, D'Allaire, S, Chorfi, Y et Rivest, J.

Annual Symposium of CRCHUM (Research Centre of University Hospital Centre of Montreal), June 16-18, 2010, Château Bromont / Bromont (QC, Canada).
Oral presentation: Neurobiology of pain and aging in osteoarthritic animals. Troncy, E.

International Osteoporosis Foundation World Congress on Osteoporosis & 10th European Congress on Clinical and Economic Aspects of Osteoporosis and Osteoarthritis (IOF WCO- ECCEO10), May 5-8, 2010, Fortezza da basso / Firenze (Italy).
Poster: Oral treatment with a Brachystemma calycinum D. Don plant extract reduces disease symptoms and the development of cartilage lesions in experimental dog asteoarthritis: inhibition of protease activated receptor-2 (PAR-2). Martel-Pelletier, J.; Boileau, C.; Caron, J.; Paré, F.; Troncy, E.; Moreau, M.; Pelletier, J.-P. Osteoporosis International, 21:349, Aug 2010.

Lecture presented April 1st 2010 at the Faculty of Dentistry of McGill University.
Oral presentation: Discovery of new pain medicines: coupling medicinal chemistry with proteomic approaches may unveil new therapeutic strategies for neuropathic pain. Beaudry, F. and Vachon, P. Invited Speaker

Association of Veterinary Anaesthetists Spring Meeting 2010, March 30-31 2010, Queens’ College – University of Cambridge / Cambridge (UK).
Oral presentation: A pilot study of the effect of environmental alterations on activity levels in dogs in an intensive care unit setting. Gent, T.; Pang, D.S.J.; Sauvage, V.; Troncy, E.; Boysen, S. Veterinary Anaesthesia and Analgesia. 37(4):5-6, Jul 2010.

49th Annual Meeting of the Society of Toxicology, March 07-11, 2010, Convention Center / Salt Lake City (Utah, United States of America).
Poster – Discussion: Qualification of cardiopulmonary safety pharmacology monitoring method using telemetry in cynomolgus monkeys evaluated with pharmaceutical modulators. Authier, S.; Mikaelian, R.; Gold, L.; Robichaud, A.; Troncy, E.
Poster – Discussion: Tri-species comparison of respiratory mechanics: Beagle dogs, Göttingens minipigs and cynomolgus monkeys. Mikaelian, R.; Gold, L.; Robichaud, A.; Troncy, E.; Authier, S.
Poster – Discussion: Electroretinography: Comparison of standard protocol in New Zeland white rabbits, Beagle dogs and Göttingens minipigs. Ponzi, C.; Authier, S.; Chaurand, F.; Troncy, E.

Association des vétérinaires en industrie animale (AVIA) février 2010
Présentation orale: Mesure de la vomitoxine (DON) et de l'ochratoxine A (OTA) au niveau du sérum et de l'urine des animaux domestiques. présentation orale. Chorfi Y.

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